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Year : 2014  |  Volume : 41  |  Issue : 3  |  Page : 211-214

Celiac disease manifesting as isolated cobalamin deficiency megaloblastic anemia: Case series and review

1 Department of Paediatrics, Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India
2 Department of Surgery, Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India

Correspondence Address:
Suresh Birur Parmeshwarappa
Department of Surgery, Subbaiah Institute of Medical Sciences, Shimoga - 577 222, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-5009.141246

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Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. It has been identified as one of the most common lifelong disorders on a worldwide basis. Enteropathy in CD is thought to be the final consequence of an abnormal immune reaction, showing features of both an innate and adaptive response to gluten prolamins. The clinical spectrum is wide, including cases with either typical intestinal or atypical extra intestinal features, or silent forms. Anemia has frequently been reported as the only manifestation or the most frequent extra-intestinal symptom of CD. The only available treatment consists in dietary exclusion of grains containing gluten.

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