CASE REPORT |
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Year : 2018 | Volume
: 45
| Issue : 1 | Page : 36-39 |
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Fatal microangiopathic hemolytic anemia: Two case reports
Majed Abdul Basit Momin1, Saroj Kumar Prusty2, Anamika Aluri2, V Soumya1
1 Department of Laboratory Medicine, Yashoda Hospital, Malakpet, Hyderabad, Telangana, India 2 Department of Department of Critical Care, Yashoda Hospital, Malakpet, Hyderabad, Telangana, India
Correspondence Address:
Majed Abdul Basit Momin Department of Laboratory Medicine, Yashoda Hospital, Malakpet Nalgonda X-Roads, Hyderabad... - 500. 036, Telangana India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jss.JSS_9_18
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The microangiopathic hemolytic anemia (MAHA) characterizing hemolytic anemia with fragmented red blood cells (RBCs) in the peripheral blood smears. Hemolytic Uremic Syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are classified under MAHA. We report two cases who presented to emergency room (ER), a 7-year-old female child who was diagnosed with atypical HUS with malignant hypertension on the basis of classic triad of hemolytic anemia, thrombocytopenia, and acute kidney injury. Second case was a 45-year-old female presented with altered sensorium, fever, and multiorgan failure. And finally diagnosed as TTP. Both the cases partially treated at private nursing home initially for few days and then referred to our hospital. This case report emphasizes the importance of correlation of emergency and laboratory physicians’ findings to approach a case of MAHA. As delay in early recognition of these conditions resulting in fatal outcome.
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