Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2020  |  Volume : 47  |  Issue : 3  |  Page : 180-184

Significance of human epidermal growth factor receptor 2 neu immunostain in head and neck squamous cell carcinoma


Department of Pathology, Employees' State Insurance Corporation Medical College, PGIMSR, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Panduranga Chikkannaiah
Department of Pathology, Employees' State Insurance Corporation Medical College, PGIMSR, Bengaluru - 560 010, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jss.JSS_60_20

Rights and Permissions

Introduction: Squamous cell carcinoma is the most common head and neck cancer. In spite of advances in the diagnosis and treatment, a prognosis still remains poor. Head-and Neck squamous cell carcinoma (HNSCC) is found to express human epidermal growth factor receptor 2 (Her 2) neu marker. Materials and Methods: The present study was conducted for a period of 1 year from January to December 2017. All the cases which have been pathologically diagnosed as HNSCC were included in the study. Results: During the study period, a total of 50 cases were observed. Male: female ratio was 1.7:1. In our study, buccal mucosa was the most common site (26'). Well-differentiated morphology was more common (36'), and 34' cases were positive for Her 2 Neu expression. Conclusion: Her 2 neu expression may not be a reliable molecular prognostic marker for HNSCC.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed156    
    Printed0    
    Emailed0    
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal