Journal of the Scientific Society

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 44  |  Issue : 3  |  Page : 140--144

Clinicopathological profile of patients with non-hodgkin's lymphoma at a regional cancer center in Northeast India


Adhikarimayum Ambika Devi, Takhenchangbam Dhaneshor Sharma, Yengkhom Indibor Singh, Hage Sonia 
 Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India

Correspondence Address:
Adhikarimayum Ambika Devi
Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal - 795 004, Manipur
India

Context: Incidence of non-Hodgkin's lymphoma (NHL) is increasing in all parts of the world, especially over the past few decades. An insight into the clinical presentation may help in the prevention, control, and treatment of NHL. Aim: To observe the clinicopathological patterns of NHL among patients in Northeast India. Subjects and Methods: A retrospective case study on 100 proven cases of NHL registered at the Regional Institute of Medical Sciences, Manipur, during the period January 2013–May 2017 was conducted, and data were reviewed and analyzed. Statistical Analysis Used: Data were analyzed using SPSS-21 and results were presented in percentages and simple frequency. Results: Majority (43.0%) of the patients were in the age group of 41 and 60 years. The mean age was 54.01 ± 18.1 years. Male:female ratio was 1.2:1. The most common presenting symptom was neck swelling (57.0%), and peripheral lymphadenopathy (76.0%) was the most common sign. Primary site distribution was nodal (57.0%) and extra-nodal NHL (43.0%). Most common nodal site involved was cervical lymph nodes (65.0%), and gastrointestinal tract (17.0%) was the most common extranodal subsite. Majority of the patients were in stage II (36.0%) at the time of diagnosis. B-cell NHL accounts for 66.0% compared to T-cell lymphoma (23.0%). Diffuse large B-cell lymphoma was the most frequent B-cell lymphoma (45.0%), and anaplastic large cell lymphoma was the most common T-cell variant (15.0%). Conclusions: A thorough insight into the clinical spectrum of NHL is necessary for optimum management and improved treatment outcome.


How to cite this article:
Devi AA, Sharma TD, Singh YI, Sonia H. Clinicopathological profile of patients with non-hodgkin's lymphoma at a regional cancer center in Northeast India.J Sci Soc 2017;44:140-144


How to cite this URL:
Devi AA, Sharma TD, Singh YI, Sonia H. Clinicopathological profile of patients with non-hodgkin's lymphoma at a regional cancer center in Northeast India. J Sci Soc [serial online] 2017 [cited 2021 Jul 26 ];44:140-144
Available from: https://www.jscisociety.com/article.asp?issn=0974-5009;year=2017;volume=44;issue=3;spage=140;epage=144;aulast=Devi;type=0